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Melatonin has been shown to have anti-inflammatory results, among a variety of actions. Melatonin lowers tissue damage during inflammatory reactions by a variety of methods. Hence melatonin, by virtue of its capacity to straight feed on hazardous totally free radicals, lowers macromolecular damages in all body organs. The free radicals and reactive oxygen as well as nitrogen species recognized to be scavenged by melatonin consist of the highly hazardous hydroxyl radical, peroxynitrite anion, and hypochlorous acid, among others. These agents all contribute to the inflammatory response and also linked tissue devastation. Furthermore, melatonin has other means to decrease the damage arising from swelling.
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